Roginolisib in Combination with JAK Inhibitors in Patients with Myelofibrosis Who are Unresponsive to Approved JAK ...
Introduction Myeloproliferative neoplasms (MPNs), including myelofibrosis (MF), are clonal diseases thought to originate from a single hematopoietic stem cell.1 In MF, gain-of-function mutations are considered driver genes (eg, JAK2, CALR, and MPL) as they …